OP16.01: First-trimester sonographic screening for aneuploidy in multiple pregnancies

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Aneuploidy screening in the first trimester.

This article reviews the performance of first trimester screening for chromosomal anomalies using various combinations of ultrasound and maternal serum biochemical modalities. Detection rates in excess of 90% can be routinely achieved for Trisomy 21, Trisomy 13, Trisomy 18 using a combination of fetal nuchal translucency (NT) thickness and maternal serum free ss-hCG and PAPP-A at 11 + 0 to 13 +...

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Prospective first-trimester screening for trisomy 21 in 30,564 pregnancies.

OBJECTIVE This study was undertaken to evaluate the performance of a 1-stop clinic for first-trimester assessment of risk (OSCAR) for trisomy 21 by a combination of maternal age, fetal nuchal translucency (NT) thickness, and maternal serum-free ss- human chorionic gonadotrophin (hCG) and pregnancy-associated plasma protein-A (PAPP-A). STUDY DESIGN OSCAR was carried out in 30,564 pregnancies a...

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Prenatal Screening for and Diagnosis of Aneuploidy in Twin Pregnancies

Objective: To provide a Canadian consensus document with recommendations on prenatal screening for and diagnosis of fetal aneuploidy (e .g ., Down syndrome and trisomy 18) in twin pregnancies . Options: The process of prenatal screening and diagnosis in twin pregnancies is complex . This document reviews the options available to pregnant women and the challenges specific to screening and diagno...

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Prenatal screening for and diagnosis of aneuploidy in twin pregnancies.

OBJECTIVE To provide a Canadian consensus document with recommendations on prenatal screening for and diagnosis of fetal aneuploidy (e.g., Down syndrome and trisomy 18) in twin pregnancies. OPTIONS The process of prenatal screening and diagnosis in twin pregnancies is complex. This document reviews the options available to pregnant women and the challenges specific to screening and diagnosis ...

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No. 261-Prenatal Screening for Fetal Aneuploidy in Singleton Pregnancies.

OBJECTIVE To develop a Canadian consensus document on maternal screening for fetal aneuploidy (e.g., Down syndrome and trisomy 18) in singleton pregnancies. OPTIONS Pregnancy screening for fetal aneuploidy started in the mid 1960s, using maternal age as the screening test. New developments in maternal serum and ultrasound screening have made it possible to offer all pregnant patients a non-in...

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ژورنال

عنوان ژورنال: Ultrasound in Obstetrics and Gynecology

سال: 2008

ISSN: 0960-7692,1469-0705

DOI: 10.1002/uog.5786